pyPESTO - Parameter EStimation TOolbox for python

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pyPESTO is a widely applicable and highly customizable toolbox for parameter estimation.

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Feature overview

pyPESTO features include:

Quick install

The simplest way to install pyPESTO is via pip:

pip3 install pypesto

More information is available here:


The documentation is hosted on


Multiple use cases are discussed in the documentation. In particular, there are jupyter notebooks in the doc/example directory.


We are happy about any contributions. For more information on how to contribute to pyPESTO check out


PESTO: Parameter estimation toolbox for MATLAB. Development is discontinued, but PESTO comes with additional features waiting to be ported to pyPESTO.